RABBIT ANTI HUMAN CD294 (N-TERMINAL) MBS224236 from MyBioSource.com

Description

MBS224236 recognises CD294, also known as chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) and GRP44. CD294 is a G protein-coupled receptor which has a high affinity for prostaglandin D2 (PGD2). CD294 is predominantly expressed on Th2 cells, basophils and eosinophils, and its activation by PDG2 mediates chemotaxis of these cells to inflammatory sites. CD294 may be a useful marker for Th2 cells, and enhances their function and signalling with a possible role in Th2 cell differentiation. PGD2 is thought to contribute to bronchoconstriction, eosinophilia and mucus production in allergic asthma, and CD294 may contribute to this disease

Product Specs
ItemRABBIT ANTI HUMAN CD294 (N-TERMINAL)
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS224236
Quantity0.05 mg
ApplicationsELISA (EIA), Immunohistology Paraffin, Western Blot (WB)
ConcentrationIgG concentration 1.0mg/ml
Conjugate/TagUnconjugated
FormatPurified
Purified IgG - liquid
ReactivityMouse (Expected from Sequence), Rat (Expected from Sequence)
TargetCD294
IsotypeIgG
Molecular Weight42,950 Da
HostRabbit
ImmunogenThis item recognises CD294, also known as chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) and GRP44.

CD294 is a G protein-coupled receptor which has a high affinity for prostaglandin D2 (PGD2).

CD294 is predominantly expressed on Th2 cells, basophils and eosinophils, and its activation by PDG2 mediates chemotaxis of these cells to inflammatory sites. CD294 may be a useful marker for Th2 cells, and enhances their function and signalling with a possible role in Th2 cell differentiation.

PGD2 is thought to contribute to bronchoconstriction, eosinophilia and mucus production in allergic asthma, and CD294 may contribute to this disease
NCBI Full Gene Nameprostaglandin D2 receptor 2
NCBI Gene AliasesGpr44, Grp45, Crth2
ClonalityPolyclonal